Wednesday, November 2, 2016

Hydrocortisone Acetate Suppositories



Pronunciation: hye-droe-KOR-ti-sone
Generic Name: Hydrocortisone Acetate
Brand Name: Examples include Anusol-HC and Hemorrhoidal-HC


Hydrocortisone Acetate Suppositories are used for:

Reducing swelling, itching, and discomfort associated with certain rectal conditions, including hemorrhoids.


Hydrocortisone Acetate Suppositories are a topical corticosteroid. It works by depressing the formation, release, and activity of different cells and chemicals that cause swelling, redness, and itching.


Do NOT use Hydrocortisone Acetate Suppositories if:


  • you are allergic to any ingredient in Hydrocortisone Acetate Suppositories

  • you are taking mifepristone

  • you have a rectal obstruction, abscess, or perforation; irritation of the peritoneum (lining of the abdomen); or fistulas

Contact your doctor or health care provider right away if any of these apply to you.



Before using Hydrocortisone Acetate Suppositories:


Some medical conditions may interact with Hydrocortisone Acetate Suppositories. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a parasitic, bacterial, fungal, or viral infection; diabetes; diarrhea; swelling of the esophagus; stomach problems; blockage or the intestine or other intestinal problems; measles; tuberculosis (TB); a positive TB skin test; chicken pox; shingles; herpes infection of the eye; ulcers; kidney problems; high blood pressure; thyroid problems; or you have received a recent vaccination

  • if you have a history of heart failure or heart attack

Some MEDICINES MAY INTERACT with Hydrocortisone Acetate Suppositories. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Barbiturates (eg, phenobarbital), carbamazepine, cholestyramine, colestipol, fluconazole, hydantoins (eg, phenytoin), lithium, rifampin, or thioamines (eg, propylthiouracil) because they may decrease Hydrocortisone Acetate Suppositories's effectiveness

  • Aprepitant, clarithromycin, estrogens (eg, estradiol), macrolide immunosuppressants (eg, tacrolimus), nefazodone, or steroidal contraceptives (eg, birth control pills) because side effects such as adrenal gland or central nervous system problems may occur

  • Anticholinesterases (eg, pyridostigmine), anticoagulants (eg, warfarin), live vaccines, macrolide immunosuppressants (eg, tacrolimus), nondepolarizing muscle relaxants (eg, vecuronium), ritodrine, or theophylline because their actions and the risk of their side effects may be increased by Hydrocortisone Acetate Suppositories

  • Anticholinesterases (eg, pyridostigmine), anticoagulants (eg, warfarin), interleukin-2, mifepristone, or nondepolarizing muscle relaxants (eg, vecuronium) because their effectiveness may be decreased by Hydrocortisone Acetate Suppositories

This may not be a complete list of all interactions that may occur. Ask your health care provider if Hydrocortisone Acetate Suppositories may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Hydrocortisone Acetate Suppositories:


Use Hydrocortisone Acetate Suppositories as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Avoid excessive handling of the suppository. It is designed to melt at body temperature.

  • Wash your hands before and after using Hydrocortisone Acetate Suppositories. If the suppository is too soft to use, put it in the refrigerator for about 15 minutes. You may also run cold water over it. Remove the wrapper. Moisten the suppository with cool water. Lie down on your side. Insert the pointed end of the suppository into the rectum. Use your finger to push it in completely.

  • If you miss a dose of Hydrocortisone Acetate Suppositories and you are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Ask your health care provider any questions you may have about how to use Hydrocortisone Acetate Suppositories.



Important safety information:


  • If your symptoms do not get better within 7 days or if they get worse, check with your doctor.

  • Do not use Hydrocortisone Acetate Suppositories for other rectal conditions at a later time.

  • Do not get Hydrocortisone Acetate Suppositories in your eyes. If you get Hydrocortisone Acetate Suppositories your eyes, immediately flush them with cool tap water.

  • Check with your doctor or pharmacist concerning the use of a stool softener or bulk laxative to help improve your symptoms.

  • Check with your doctor before having vaccinations while you are using Hydrocortisone Acetate Suppositories.

  • Hydrocortisone Acetate Suppositories may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.

  • Hydrocortisone Acetate Suppositories should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Hydrocortisone Acetate Suppositories while you are pregnant. It is not known if Hydrocortisone Acetate Suppositories are found in breast milk. If you are or will be breast-feeding while you use Hydrocortisone Acetate Suppositories, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Hydrocortisone Acetate Suppositories:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Inflamed hair follicles; loss of skin color; mild irritation or dryness of the skin.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); infection; rectal pain, burning, itching, bleeding, or irritation not present before using Hydrocortisone Acetate Suppositories.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.



If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Hydrocortisone Acetate Suppositories may be harmful if swallowed.


Proper storage of Hydrocortisone Acetate Suppositories:

Store Hydrocortisone Acetate Suppositories at room temperature, below 86 degrees F (30 degrees C). Store away from heat, moisture, and light. Do not freeze. Do not store in the bathroom. Keep Hydrocortisone Acetate Suppositories out of the reach of children and away from pets.


General information:


  • If you have any questions about Hydrocortisone Acetate Suppositories, please talk with your doctor, pharmacist, or other health care provider.

  • Hydrocortisone Acetate Suppositories are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Hydrocortisone Acetate Suppositories. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Hydrocortisone Acetate resources


  • Hydrocortisone Acetate Use in Pregnancy & Breastfeeding
  • Hydrocortisone Acetate Drug Interactions
  • Hydrocortisone Acetate Support Group
  • 15 Reviews for Hydrocortisone Acetate - Add your own review/rating


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